The Manitoba Museum is the province's largest heritage centre renowned for its combined human and natural heritage themes. The institution shares knowledge about Manitoba, the world and the universe through its collections, exhibitions, publications, on-site and outreach programs, Planetarium shows and Science Gallery exhibits.

The Museum's collections reflect the heritage of Manitoba and other regions of the world. Eight interpretive galleries explore the history and environment of the province from its northern Arctic coast to its southern prairie grasslands. The Museum is noted for its Urban Gallery, which recreates Winnipeg in the 1920s, and the full-size replica ship Nonsuch, whose voyage in 1668 led to the founding of the Hudson's Bay Company.